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The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice
Published on: November 1, 2015
Neonatal lupus erythematosus
Joanna M Burch1, Lela A Lee, William L Weston
1University of Colorado Health Sciences Center, Denver, CO, USA.
Dermatology Nursing
|July 9, 2002
Abstract:
Neonatal lupus erythematosus is associated with cutaneous lesions, CHB, hepatic disease, and thrombocytopenia. IgG antibodies to Ro and/or La cross the placenta and participate in the development of the clinical manifestations. Mothers of babies with NLE are likely to develop collagen vascular diseases with time. Infants with NLE are at risk to develop other autoimmune diseases during childhood or adolescence.