Internal initiation sites of de novo RNA synthesis within the hepatitis C virus polypyrimidine tract

Charles Pellerin1, Sylvain Lefebvre, Michael J Little

  • 1Department of Biological Sciences, Boehringer Ingelheim (Canada) Ltd., Research and Development, 2100 rue Cunard, Laval, Qué., Canada H7S 2G5.

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Initiation of Translation02:33

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Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
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