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Endometrial biopsies using small-diameter hysteroscopes and 5F instruments: how can we obtain enough material for a
S Bettocchi1, R Di Venere, N Pansini
1Department of General and Specialist Surgical Sciences, Section of Obstetrics and Gynecology A, University of Bari Policlinico, Piazza Giulio Cesare 11, Bari 70124, Italy.
Study Objective:
To evaluate the quantity of biopsy tissue obtained by hysteroscopic grasp technique compared with classic punch technique.
Design:
Observational study (Canadian Task Force classification II-2).
Setting:
University hospital.
Patients:
One thousand two hundred seventy-six women.
Intervention:
Targeted biopsies performed in an office setting using two biopsy forceps, classic spoon and crocodile, and two methods, classic punch and grasp technique.
Measurements And Main Results:
With either biopsy forceps, the mean increase in amount of tissue obtained by grasp technique compared with punch technique was statistically significant (p <0.005). With grasp technique, the mean amount of tissue obtained was even larger with crocodile than with spoon forceps.
Conclusion:
Targeted biopsy, when performed with the appropriate instrument and applying correct technique, can provide the pathologist with a large amount of tissue (mean 5.7 mm2) that is invariably adequate for histologic examination.