[Clinical results of specialized prophylactic mammography screenings of industrial workers]

Specialized mammographic screenings of 61,276 industrial workers of the City of Perm and Perm Region were carried out in 1991-1999. Examinations included palpation, mammography and ultrasound (in some patients), aspiration biopsy and cytological analysis of nipple discharge, if necessary. Various pathological sites were identified in 9,126 (14.9%). Diffuse mastopathies were diagnosed in 7,286 (11.9%), mostly in women aged 31-50 (5,239; 72%). Nodal tumors (cancer, localized fibrocytic disease, fibroadenoma, cysts and lymphomas) were detected in 1,840 (3%). Their frequency ranged 2.6-3.3% in all age-brackets: causation by fibroadenoma--in the younger women, cancer--elderly women. Breast cancer was reported in 62 (0.1% of all screenees; 0.7% of patients, and 3.4% of patients with locally-advanced tumors). Cancer stage I was identified in 31 (50%), stage II--25 (40.3%), and stage III--6(9.7%). Hence, it may be assumed that early-onset cancers accounted for 90.3% while tumor process remained localized within the gland in 72.2%. Out of 509 patients followed-up after surgery for benign tumors, 207 (40.5%) revealed signs of proliferation and 12 (2.4%)--dysplasia. These findings point to the prophylactic and therapeutic value of mammography for breast cancer control.