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Defining hormesis: comments on Calabrese and Baldwin (2002)
1EVS Environment Consultants, North Vancouver, British Columbia, Canada. pchapman@attglobal.net
Human & Experimental Toxicology
|July 10, 2002
Abstract:
The definition of hormesis should not include non-scientific judgments as to beneficial or harmful effects. Evaluating the significance of hormesis is a separate issue that ultimately requires risk:risk comparisons, particularly since the evolutionary basis for hormesis appears to be Lamarkian rather than Darwinian. It is arguable whether 'hormesis' is the correct umbrella term for all low-dose exposure responses, in particular those at higher organization levels than single species, or whether it includes arousal responses.