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Iron status: a possible risk factor for the first febrile seizure
Azhar S Daoud1, Anwar Batieha, Faisel Abu-Ekteish
1Department of Pediatrics, Jordan University of Science and Technology, Irbid. daoud@just.edu.jo
Purpose:
We conducted a controlled study to investigate the relation of iron status and first febrile seizure (FFS).
Methods:
Measures of iron sufficiency including hemoglobin concentration (HB), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and plasma ferritin (PF) were prospectively measured in 75 children with FFS and compared with 75 controls matched for age and sex with febrile illnesses without convulsions.
Results:
Mean ferritin level was significantly lower in cases with FFS (29.5 +/- 21.3 microg/L) than in controls (53.3 +/- 37.6 microg/L) with p = 0.0001. The proportion of subjects with a PF level
Conclusions:
PF level was significantly lower in children with FFS than in the reference group, suggesting a possible role for iron insufficiency in FFS.