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Updated: Aug 6, 2026

Isolation of Viral Replication Compartment-enriched Sub-nuclear Fractions from Adenovirus-infected Normal Human Cells
Published on: November 12, 2015
[The inhibiting action of superhigh-frequency millimeter waves on adenovirus (author's transl)]
Abstract:
Virological and biochemical analysis was employed for comparative studies of the content of protein in continuous cultures of human embryo kidney cells (RH line) infected with adenovirus type 1, intact and irradiated with electromagnetic waves of UHF in the range of 5 divided by 8 mm at the density of power current of the order of 4 mW. When the cells were inoculated with intact virus, a cytopatic effect, a decrease in the content of protein by 4 hours postinfection and further decrease up to 72 hrs were observed. After infection with irradiated adenovirus the development of the infectious process and associated changes in the protein content were observed only by 24 hours and then up to 72 hours there was a delay in the development of virus infection as compared with controls. The experimental data indicate different response of RH cells to infection with irradiated and intact adenovirus, namely, that UHF of the millimeter range (lambda=6.50 mm) exert a specific effect on the infectious activity of adenovirus as manifested by changes in cell metabolism after infection with irradiated virus.
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