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Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma
T J Postma1, M Klein, C C P Verstappen
1Department of Neurology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands. TJ.Postma@vumc.nl
Neurology
|July 10, 2002
Abstract:
Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.