[Histobiopsy of bone marrow (author's transl)]

The histobiopsy of the bone marrow is more and more included in clinicohaematological diagnostics. It has better diagnostic possibilities than the cytology of smears (aspiration biopsy). The specimen is taken from the iliac crest by puncture or the milling method. The sample can be considered representative of the whole bone marrow with regard to the normal quantity and quality. The pathologist ordinarily per forms the processing and assessment of the specimens in a desirably constructive cooperation with the clinical haematologist. The paper presents a condensed review of the histological technics and the recording of features in bone marrow sections, the indications for bone marrow histobiopsy, the results (2769 cases of literature and 496 own cases), and the clinical significance of human bone marrow histobiopsy.