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Preventing drug-related morbidity--determining valid indicators.

C J Morris1, J A Cantrill, C D Hepler

  • 1The Drug Usage and Pharmacy Practice Group, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, UK. caroline.j.morris@man.ac.uk

International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care
|July 11, 2002
PubMed
Summary

This study adapted US indicators for preventable drug-related morbidity for UK primary care. Consensus was reached on 29 indicators, highlighting healthcare system differences.

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Area of Science:

  • Pharmacovigilance and patient safety
  • Health services research
  • Medication safety indicators

Background:

  • Preventable drug-related morbidity poses a significant burden on healthcare systems.
  • Existing indicators developed in the US require validation for UK healthcare contexts.
  • Adapting international indicators is crucial for improving medication safety globally.

Purpose of the Study:

  • To validate a series of US-developed indicators for preventable drug-related morbidity for use in the UK.
  • To assess the applicability and consensus of these indicators within the UK primary care setting.
  • To identify potential differences in clinical perspectives between US and UK healthcare professionals.

Main Methods:

  • A two-round Delphi questionnaire survey was employed.

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  • Preliminary validation of indicators was conducted at the University of Manchester School of Pharmacy.
  • A purposively selected sample of UK general practitioners (n=6) and primary care pharmacists (n=10) participated.

    • Main Results:

    • Following preliminary validation, 37 of 57 US indicators were retained.
    • The Delphi panel generated 16 new indicators in the first round.
    • Consensus was achieved for 29 indicators (19 US-derived, 10 new) after the second round.

    Conclusions:

    • The Delphi process revealed differences in clinical and philosophical viewpoints between US and UK healthcare professionals.
    • Further validation and operationalization of indicators in primary and secondary care are ongoing.
    • Developing prospective, medical-record-based indicators can reduce the burden of drug-related morbidity.