[Vaginal cytological studies on the new delayed-action estrogen-ethinylestradiol sulfonate]

The colpocytologic efficacy of a new estrogen - ethinylestradiolsulfonate - has been studied in postmenopausal and fertile women. According to the depot character of the compound, ranging between ethinylestradiol and quinestrol, it exhibits a high and prolonged proliferative effect on the atropich vaginal epithelia. The weekly application of 1 mg of the substance in a contraceptive regimen causes a high grade of maturation with considerable individual differences. A single dose of 1 mg ethinylestradiolsulfonate quickly influences conditions of estrogen difficiency in the vaginal epithelia.