Related Experiment Video
Updated: Sep 30, 2026

Electric Cell-substrate Impedance Sensing for the Quantification of Endothelial Proliferation, Barrier Function, and Motility
Published on: March 28, 2014
Improvement of the accuracy by the measurement of the electrical cell membrane parameters
1Institute of Physiology, Czech Academy of Sciences, Prague. Rohlicek@biomed.cas.cz
Abstract:
The electrical parameters of the cell membrane are mostly estimated employing ac methods. The measurement is based on the analysis of the current(s) flowing through an access resistance and the membrane. A current/potential transducer is used at the input of the device. The parameters of this transducer, especially its feedback capacity, degrades the accuracy of the measurement and hence diminishes the suppression of mutual influences of the individual parameters. The paper suggests a possible software correction and is supplemented by remarks for practical application.
Related Concept Videos
Patch Clamp
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...
Potentiometry: Membrane Electrodes
Applications of EMF Measurements

