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Rhodium-catalyzed approach to Mannich-type products using aldimine, alpha,beta-unsaturated ester, and hydrosilane
Takako Muraoka1, Shin-ichi Kamiya, Isamu Matsuda
1Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University, Chikusa, Nagoya 464-8603, Japan.
Abstract:
A rhodium-catalyzed method for the synthesis of beta-amino esters was accomplished in a one-pot procedure from aldimine, alpha,beta-unsaturated ester and hydrosilane.