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Pathological and clinical aspects of the diseases caused by Malassezia species
1Dr. Juhász Tamás Clinic for Small Animals, Ecseri út 6, H-1098 Budapest, Hungary.
Abstract:
From veterinary point of view Malassezia pachydermatis has the greatest significance. It has been standing in the focus of interest since the early 1990s, mostly because of the frequency of otitis externa and dermatitis caused by this yeast in dogs. This is the only lipid-independent species in the genus Malassezia. It can be found in very large proportion on the skin of healthy animals, but can be isolated in much greater number from diseased dogs. It often causes illness together with other pathogens (e.g. Staphylococcus intermedius). Some breeds are predisposed. In addition to the treatment of the accidental concurrent diseases, therapy consists of systemic and/or topical antimicrobial treatment. Ketoconazole is used most frequently. Malassezia pachydermatis plays also a role in the skin disorders of other carnivores. It has little zoonotic potential, it can be dangerous to immunocompromised humans. The other Malassezia species have little veterinary importance, although M. sympodialis and M. globosa were isolated from asymptomatic animals (mostly cats) and from mixed infections.
Insights
Malassezia pachydermatis is a significant yeast in veterinary medicine, frequently causing skin and ear infections in dogs. While common on healthy animals, it increases in diseased dogs and can affect other carnivores.
Area of Science:
- Veterinary Dermatology
- Microbiology
- Mycology
Background:
- Malassezia pachydermatis is a yeast of significant veterinary importance, particularly in canine dermatology.
- It is frequently implicated in cases of otitis externa and dermatitis in dogs.
- This yeast is lipid-independent and commonly found on the skin of healthy animals, but at higher concentrations in diseased individuals.
Purpose of the Study:
- To review the veterinary significance of Malassezia pachydermatis.
- To discuss its role in canine and other carnivore skin disorders.
- To highlight its etiological role, predisposing factors, and treatment approaches.
Main Methods:
- Literature review focusing on veterinary studies concerning Malassezia pachydermatis.
- Analysis of its prevalence in healthy versus diseased animals.
- Examination of co-infections and therapeutic strategies.
Main Results:
- Malassezia pachydermatis is a primary cause of otitis externa and dermatitis in dogs, often in conjunction with other pathogens.
- Certain dog breeds exhibit predispositions to Malassezia-related skin conditions.
- Therapeutic interventions commonly include systemic and topical antimicrobial treatments, with ketoconazole being frequently used.
Conclusions:
- Malassezia pachydermatis is a key pathogen in veterinary dermatology, especially for dogs.
- While it has low zoonotic potential, it can pose risks to immunocompromised humans.
- Other Malassezia species have limited veterinary significance, though some have been isolated from animals.
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