Bioinformatics: a holistic approach to drug discovery

Clinical utility and cost-effectiveness of BeginNGS newborn screening by genome sequencing and standard newborn screening for severe childhood genetic diseases: an adaptive, international and comparative clinical trial.

BMJ open·2025

Assessment of putative protein targets derived from the SARS genome.

FEBS letters·2003

Drug type contributions to pharmaceutical innovation: A USA-China comparative analysis.

Drug discovery today·2026

Covalent small-molecule RNA targeting in Alzheimer's disease: computational strategies, challenges and opportunities.

Drug discovery today·2026

Can agentic AI dent Eroom's Law? Large reasoning models across the drug discovery and development pipeline.

Drug discovery today·2026

Tumor hypoxia: Molecular pathways and therapeutic interventions.

Drug discovery today·2026

Degraders of histone lysine methyltransferases: Progress, challenges, and opportunities.

Drug discovery today·2026

Single-cell and spatial transcriptomic insights into fibrotic mechanisms and therapeutic opportunities.

Drug discovery today·2026

Biophysical and Cellular Assays for the Evaluation of Peptidomimetic Inhibitors Based on Degron Sequences.

Methods in molecular biology (Clifton, N.J.)·2026

PSGS-Drug: Generation-Time Dual-Pocket Guidance for Non-Symmetric Dual-Target Molecular Design.

Journal of chemical information and modeling·2026

ARID-sf: A Physics-Informed Deep Learning Scoring Function to Improve Antibody-Antigen Docking Model Ranking.

Journal of chemical information and modeling·2026

Geometric Deep Learning-Based Drug Design Models for Small-Molecule Drug Discovery.

Molecular informatics·2026

QSAR, molecular dynamics, and biological evaluation of novel myeloperoxidase inhibitors via ligand-based pharmacophore modeling as potential anticancer agents.

Journal of computer-aided molecular design·2026

A hierarchically organized communication network underlies kinetic allostery in SARS-CoV-2 Mpro.

International journal of biological macromolecules·2026

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Bioinformatics: a holistic approach to drug discovery

Related Concept Videos

Clinical utility and cost-effectiveness of BeginNGS newborn screening by genome sequencing and standard newborn screening for severe childhood genetic diseases: an adaptive, international and comparative clinical trial.

Assessment of putative protein targets derived from the SARS genome.

Drug type contributions to pharmaceutical innovation: A USA-China comparative analysis.

Covalent small-molecule RNA targeting in Alzheimer's disease: computational strategies, challenges and opportunities.

Can agentic AI dent Eroom's Law? Large reasoning models across the drug discovery and development pipeline.

Tumor hypoxia: Molecular pathways and therapeutic interventions.

Degraders of histone lysine methyltransferases: Progress, challenges, and opportunities.

Single-cell and spatial transcriptomic insights into fibrotic mechanisms and therapeutic opportunities.

Biophysical and Cellular Assays for the Evaluation of Peptidomimetic Inhibitors Based on Degron Sequences.

PSGS-Drug: Generation-Time Dual-Pocket Guidance for Non-Symmetric Dual-Target Molecular Design.

ARID-sf: A Physics-Informed Deep Learning Scoring Function to Improve Antibody-Antigen Docking Model Ranking.

Geometric Deep Learning-Based Drug Design Models for Small-Molecule Drug Discovery.

QSAR, molecular dynamics, and biological evaluation of novel myeloperoxidase inhibitors via ligand-based pharmacophore modeling as potential anticancer agents.

A hierarchically organized communication network underlies kinetic allostery in SARS-CoV-2 Mpro.

Related Experiment Videos

Bioinformatics: a holistic approach to drug discovery

Related Concept Videos

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