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MR pattern of hyperacute cerebral hemorrhage
Max Wintermark1, Philippe Maeder, Marc Reichhart
1Department of Diagnostic and Interventional Radiology, University Hospital, Lausanne, Switzerland. Max.Wintermark@chuv.hospvd.ch
Journal of Magnetic Resonance Imaging : JMRI
|July 12, 2002
Summary
This study reports the earliest magnetic resonance (MR) appearance of hyperacute cerebral hemorrhage in two stroke patients receiving thrombolytic therapy. The findings reveal unique MR characteristics of early intracerebral bleeding.
Area of Science:
- Neurology
- Radiology
- Medical Imaging
Background:
- Cerebral hemorrhage detection on magnetic resonance (MR) imaging is influenced by hemoglobin degradation products and their location.
- Thrombolytic therapy is a critical treatment for acute ischemic stroke.
Observation:
- Two patients with acute stroke undergoing thrombolytic therapy were monitored with cerebral MR during their hospital stay.
- Hyperacute cerebral hemorrhage was detected during the MR survey in both patients.
Findings:
- The observed cerebral hemorrhage represented the earliest MR appearance of hyperacute intracerebral bleeding reported to date.
- Key MR features included increased diffusion properties and a persistent susceptibility effect on perfusion-weighted imaging (PWI) series.
Implications:
- These findings may refine the understanding of early intracerebral bleeding detection using advanced MR techniques.
- The study highlights the importance of serial MR monitoring in patients receiving thrombolytic therapy for stroke.
- This early detection capability could potentially impact patient management and outcomes in acute stroke care.