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Published on: September 20, 2018
Dacryoadenitis as the earliest presenting manifestation of systemic Wegener's granulomatosis
M Soheilian1, A Bagheri, M Aletaha
1Ophthalmology Department and Eye Research Labbafinejad Medical Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran. Labbafi@hotmail.com
Purpose:
To report a case presenting with dacryoadenitis as the earliest manifestation of systemic Wegener's granulomatosis (WG).
Design:
Observational case report.
Methods:
A 41-year-old woman initially presented symptoms of bilateral dacryoadenitis. She subsequently developed upper and lower respiratory tract involvement, scleritis and keratitis.
Results:
Cytoplasmic antineutrophil antibody (c-ANCA) titer was positive. The lacrimal gland and lung biopsies were consistent with WG. The patient responded well to cyclophosphamide and prednisolone.
Conclusions:
Dacryoadenitis maybe the earliestpresenting manifestation of WG andprompt immunosuppressive chemotherapy may control it preventing the limited disease from progressing to a complete form and reducing its morbidity and mortality.
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