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Doppler echocardiographic evaluation of right ventricular diastolic function in hypertrophic cardiomyopathy

G K Efthimiadis1, G E Parharidis, H I Karvounis

  • 11st Department of Cardiology, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece.

European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology
|July 13, 2002
PubMed

Insights

Right ventricular diastolic function is impaired in hypertrophic cardiomyopathy patients, showing abnormal relaxation. Diastolic indices of the right ventricle correlate with those of the left ventricle.

Area of Science:

  • Cardiology
  • Cardiovascular Physiology

Background:

  • Left ventricular diastolic function in hypertrophic cardiomyopathy (HCM) is well-documented.
  • Right ventricular (RV) diastolic function in HCM remains understudied.

Purpose of the Study:

  • To investigate RV diastolic function in patients with HCM.
  • To utilize Doppler echocardiography for assessing RV diastolic parameters.

Main Methods:

  • Studied 20 HCM patients and 20 healthy controls.
  • Measured left and right ventricular diastolic indices using pulsed Doppler echocardiography.
  • Assessed RV-E/A ratio, isovolumic relaxation time, and deceleration time.

Main Results:

  • HCM patients exhibited significantly lower RV-E/A ratio (P<0.04) and prolonged RV isovolumic relaxation time (P<0.001) and deceleration time (P<0.01) compared to controls.
  • Significant correlations were found between RV and left ventricular (LV) deceleration times (r=0.78).
  • RV-E/A ratio correlated with left atrial filling fraction (r=-0.55), and right atrial filling fraction correlated with left atrial filling fraction (r=0.75).

Conclusions:

  • RV diastolic function is impaired in HCM patients, indicating abnormal relaxation.
  • RV diastolic indices demonstrate a strong correlation with LV diastolic indices.
Abstract

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