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Involvement of the hypothalamic-pituitary-adrenal axis in children with oligoarticular-onset idiopathic arthritis

P Picco1, M Gattorno, M P Sormani

  • 1Department of Pediatric Rheumatology, G. Gaslini Institute, Genova, Italy. Paolopicco@ospedale-gaslini.ge.it

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Autoimmune Disorders

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Concept and Mechanism of Autoimmune Diseases
The immune system...
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T Cell Types and Functions

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Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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Cushing Syndrome II: Pathophysiology

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The JAK-STAT Signaling Pathway

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Adrenal Gland Disorders

Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
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Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...