Some structure-activity relationships of iodophorous iodine complex compounds. Part II. Biological

The iodophors described in the part I [5] were subjected to studies in order to determine their antibacterial activity against Staphylococcus aureus 209P, Pseudomonas aeruginosa and Escherichia coli. General effectiveness was evaluated and useful concentration was determined using the FDA (Food and Drug Administration) method and a test with mechanical carriers. The obtained results were compared with respective values for a commercial product--Iosan (Ciba--Geigy); we found that properties of the products were comparable. The possibility of removal of iodophors, labelled with 131I, from glass, rubber and polystyrene surfaces was also examined. We found that the iodophors are suitable for disinfection of glass and drug packages.