Related Experiment Video
Updated: Sep 30, 2026

Investigating Functional Regeneration in Organotypic Spinal Cord Co-cultures Grown on Multi-electrode Arrays
Published on: September 23, 2015
Spontaneous electromyographic activity in spinal cord lesions
1Department of Clinical Neurophysiology, Instituto de Investigaciones Neurológicas Dr. Raúl Carrea (FLENI), Montañeses 2325, 1428 Buenos Aires, Argentina. mnogues@fleni.org.ar
Abstract:
Different types of spontaneous activity may be found during electromyographic examinations in patients with spinal cord diseases. Syringomyelia and intramedullary tumor patients may show continuous motor unit activity, synchronous motor unit potentials, myokymic discharges, segmental and propriospinal myoclonus, and respiratory synkinesis. These types of discharges are less commonly encountered in other types of spinal cord lesions. It is suggested that the derangement of inhibitory mechanisms by a central spinal cord lesion may favor the appearance of abnormal spontaneous activity. An increase in the excitability of spinal motor neurons is probably the basic underlying mechanism.

