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A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.
06:55

A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.

Published on: November 7, 2018

[Typhoid fever and Salmonella gastroenteritis in children (author's transl)]

F Hawkins Carranza, T Sainz Martín, A Scarpellini

    Anales Espanoles De Pediatria
    |November 1, 1975
    PubMed

    Insights

    This study on childhood salmonellosis confirms gastroenteritis is more common in young children, while typhoid fever affects older children. Antibiotic resistance is a growing concern.

    Area of Science:

    • Pediatric infectious diseases
    • Bacteriology
    • Clinical microbiology

    Context:

    • Salmonellosis presents as typhoid fever or gastroenteritis in children.
    • Age influences the clinical presentation of salmonellosis.
    • Antibiotic resistance is an emerging challenge in treating salmonellosis.

    Purpose:

    • To investigate the clinical features and serologic diagnosis of salmonellosis in hospitalized children.
    • To evaluate the effectiveness of different antimicrobial agents against Salmonella strains.
    • To highlight the relationship between Salmonella serogroup D and typhoid fever.

    Summary:

    • The study analyzed 25 hospitalized children with salmonellosis, differentiating between typhoid fever and gastroenteritis.
    • Gastroenteritis was prevalent in children under 3 years, whereas typhoid fever was more common in older children.
    • Limited diagnostic value was found for white cell count and spleen enlargement. Serologic tests were appraised, noting the association between Salmonella group D and typhoid fever.
    • The study examined the efficacy of ampicillin, chloramphenicol, and trimethoprim-sulfamethoxazole, considering increasing antibiotic resistance.

    Impact:

    • Provides age-specific insights into salmonellosis presentation in children.
    • Informs diagnostic strategies by evaluating serologic tests and clinical markers.
    • Highlights the critical issue of antibiotic resistance in Salmonella treatment, guiding therapeutic choices.

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