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Dental and skeletal stem cells: potential cellular therapeutics for craniofacial regeneration
Paul H Krebsbach1, Pamela Gehron Robey
1University of Michigan School of Dentistry, Department of Oral Medicine, Pathology and Oncology, Ann Arbor 48109-1078, USA. paulk@umich.edu
Abstract:
The study of stem cells has received considerable attention since the discovery that adult stem cells have the capacity to form many different tissue types. Technical advances have helped identify potential stem cells, and their capacity for regenerating tissues is being studied in transplantation models. Further study of the isolation, nature, and differentiation potential of stem cells will likely have a positive impact on our understanding of human development and regenerative medicine. This review highlights the difference between embryonic and adult stem cells and discusses the potential use of these cells for cellular therapeutics for craniofacial regeneration.
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