Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Advances in proteomic technologies.

Martin L Yarmush1, Arul Jayaraman

  • 1Center for Engineering in Medicine/Surgical Services, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA. ireis@sbi.org

Annual Review of Biomedical Engineering
|July 16, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Aryl hydrocarbon Receptor Nuclear Translocator 2: A Forgotten Per-ARNT-Sim Transcription Factor.

Toxicological sciences : an official journal of the Society of Toxicology·2026
Same author

Protein Diffusion in Electroporation-Based Biopsy: Quantifying Protein Transport From Human Skin for Skin Liquid Sampling With Electroporation.

Biotechnology and bioengineering·2026
Same author

The organ-on-a-chip mirage: Animal replacement, plastic channels, and plastic claims: <i>The False Narrative Behind the War on Animal Research</i>.

Innovation and emerging technologies·2026
Same author

Pesco-Vegetarian Food Components Promote Colonocyte Ferroptosis in Preclinical Mouse Models and a Randomized Crossover Trial in Healthy Human Adults.

The Journal of nutrition·2025
Same author

Mechanotyping of Organoids for Assessing Drug-Induced Injuries.

Advanced materials (Deerfield Beach, Fla.)·2025
Same author

Correction: Comparing two extracellular additives to facilitate extended storage of red blood cells in a supercooled state.

Frontiers in physiology·2025
Same journal

Physics-Informed Machine Learning in Biomedical Science and Engineering.

Annual review of biomedical engineering·2026
Same journal

Advancements and Challenges in Computer-Assisted Medical Interventions for Image-Guided Prostate Cancer Treatments.

Annual review of biomedical engineering·2026
Same journal

Recent Advances in mRNA Therapeutic Cancer Vaccines.

Annual review of biomedical engineering·2026
Same journal

Artificial Intelligence-Based Analysis of Laparoscopic Imaging for Intraoperative Surgical Decision Support.

Annual review of biomedical engineering·2026
Same journal

Viscoelasticity of the Heart: An Overview of Viscoelastic Measurements at Different Scales.

Annual review of biomedical engineering·2026
Same journal

Digital Twins for Biofluids.

Annual review of biomedical engineering·2026
See all related articles

Modern proteomics utilizes high-throughput technologies to identify proteins and map cellular interactions. This review covers current experimental and computational methods for characterizing proteomes, identifying proteins, and determining protein function.

Area of Science:

  • Proteomics
  • Biochemistry
  • Genomics

Background:

  • The human genome project has expanded proteomics beyond protein identification to include structure, function, and interactions.
  • High-throughput approaches define modern proteomics, integrating established and emerging technologies.

Purpose of the Study:

  • To review the current status of experimental and computational technologies in proteomics.
  • To discuss the application of these technologies in characterizing proteomes, identifying proteins, and determining protein function.
  • To explore the development of new proteomic technologies.

Main Methods:

  • Two-dimensional gel electrophoresis
  • Mass spectrometry
  • Yeast two-hybrid screens

Related Experiment Videos

  • Computational prediction programs

    • Main Results:

    • High-throughput proteomics enables comprehensive study of cellular processes.
    • Integration of advanced analytical, biochemical, engineering, and computational techniques drives proteomic advancements.

    Conclusions:

    • Established and emerging technologies are crucial for understanding protein structure and function.
    • Continued technological integration is vital for advancing proteomics and cellular biology.