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Alternative splicing of LYT1 transcripts in Trypanosoma cruzi
Rebeca Manning-Cela1, Antonio González, John Swindle
1Departamento de Biomedicina Molecular, Centro de Investigación y de Estudios Avanzados del IPN, México, D.F., México.
Infection and Immunity
|July 16, 2002
Abstract:
As a result of alternative trans splicing, three distinct LYT1 mRNAs are produced in Trypanosoma cruzi, two encoding the full-length LYT1 protein and the third encoding a truncated LYT1 protein lacking a possible signal sequence. Analysis of the three mRNAs in different developmental forms of the parasite revealed that the alternative processing events were regulated differently during the parasite life cycle.