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Osteoporosis in men: pathophysiology, evaluation, and therapy
Elizabeth Burgess1, Mark S Nanes
1Emory University School of Medicine and VA Medical Center, Atlanta, Georgia, USA.
Current Opinion in Rheumatology
|July 16, 2002
Summary
Osteoporosis affects men significantly. This review explores gender-specific screening, diagnosis, and treatment strategies for male osteoporosis, presenting a clinical algorithm.
Area of Science:
- Bone health and endocrinology
- Men's health and geriatrics
- Pharmacology and therapeutics
Background:
- Osteoporosis is a prevalent skeletal disorder with significant health implications for men.
- Advances in understanding pathophysiology and treatment enable gender-specific approaches.
- Current clinical practice lacks comprehensive guidelines for male osteoporosis management.
Purpose of the Study:
- To review current data on osteoporosis in men.
- To discuss controversies in screening and treatment thresholds for men.
- To present an evidence-based clinical treatment algorithm for male osteoporosis.
Main Methods:
- Comprehensive literature review of osteoporosis in men.
- Analysis of recent clinical trial data pertaining to male osteoporosis treatments.
- Development of a clinical algorithm based on current evidence and expert consensus.
Main Results:
- Osteoporosis diagnosis and management in men differ from women.
- Screening and treatment guidelines for men remain debated.
- Recent data support specific therapeutic options for male osteoporosis.
Conclusions:
- A gender-specific approach to male osteoporosis is warranted.
- Further research is needed to clarify screening and treatment controversies.
- The proposed clinical algorithm provides a framework for managing osteoporosis in men.