Related Experiment Videos
Hydrodynamic function of the second-generation mitroflow pericardial bioprosthesis.
Louise M Jennings1, Abdusalam El-Gatit, Zsolt L Nagy
1Yorkshire Heart Centre, Leeds, United Kingdom.
The Annals of Thoracic Surgery
|July 18, 2002
Summary
The Mitroflow Synergy stented pericardial bioprosthesis demonstrates good hydrodynamic function, with larger sizes offering better effective orifice area. This valve shows potential for excellent aortic position performance, especially in older patients.
Area of Science:
- Cardiovascular Surgery
- Biomedical Engineering
- Prosthetic Valve Design
Background:
- The study investigates the hydrodynamic function of Mitroflow Synergy stented pericardial bioprostheses.
- Comparison is made with previous studies on free-sewn bioprostheses using an in vitro aortic root model.
Purpose of the Study:
- To evaluate the hydrodynamic performance of smaller Mitroflow Synergy stented pericardial bioprostheses.
- To compare their performance against existing bioprosthetic valves.
Main Methods:
- Three sizes (19, 21, 23 mm) were tested in fresh tissue aortic roots within a pulsatile flow simulator.
- Leaflet dynamics were analyzed using high-speed imaging; pressure difference, flow, orifice area, regurgitant volume, and energy loss were measured.
Main Results:
- Effective orifice area increased with valve size, showing improved performance.
- All valve sizes exhibited competent closure with no regurgitant volume.
- Mitroflow valves had superior leaflet deformation compared to other tested bioprostheses.
Conclusions:
- The Mitroflow Synergy stented pericardial bioprosthesis exhibits promising in vivo hemodynamic performance.
- Its favorable hemodynamics and ease of implantation suggest suitability for the aortic position, particularly in elderly patients with small aortic annuli.