Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hydrogen bridges in crystal engineering: interactions without borders.

Gautam R Desiraju1

  • 1School of Chemistry, University of Hyderabad, Hyderabad 500 046, India. desiraju@uohyd.ernet.in

Accounts of Chemical Research
|July 18, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Is a data deluge dampening our idea generation capability?

Innovation (Cambridge (Mass.))·2025
Same author

Heterosynthons, Solid Form Design and Enhanced Drug Bioavailability.

Angewandte Chemie (International ed. in English)·2022
Same author

Crystal engineering in <b>IUCrJ</b> 2021: interactions, structures, properties.

IUCrJ·2022
Same author

Reply to the 'Comment on "Trimorphs of 4-bromophenyl 4-bromobenzoate. Elastic, brittle, plastic"' by J. J. Whittaker, A. J. Brock, A. Grosjean, M. C. Pfrunder, J. C. McMurtrie and J. K. Clegg, <i>Chem. Commun.</i>, 2021, <b>57</b>, DOI: 10.1039/D0CC07668F.

Chemical communications (Cambridge, England)·2021
Same author

Synthetic Approaches to Halogen Bonded Ternary Cocrystals.

Angewandte Chemie (International ed. in English)·2021
Same author

Crystal engineering in IUCrJ: from 'the' crystal structure to 'a' crystal structure.

IUCrJ·2021

Hydrogen bonds are electrostatic interactions where hydrogen bridges two atoms. The concept has broadened to include weaker interactions, suggesting "hydrogen bridge" better describes their varied nature.

Area of Science:

  • Chemistry
  • Materials Science
  • Solid-State Physics

Background:

  • Hydrogen bonds (X-H...A) involve a hydrogen atom attracted to two other atoms, acting as a bridge.
  • Traditionally viewed as highly electrostatic, sometimes with covalent character, increasing with X and A electronegativity.
  • The definition has evolved to encompass weaker interactions retaining some electrostatic character.

Purpose of the Study:

  • To highlight common features across diverse hydrogen bonds observed in the solid state.
  • To propose 'hydrogen bridge' as a more fitting descriptor for these interactions.
  • To emphasize the spectrum of interactions, from strong to weak, including van der Waals forces.

Main Methods:

  • Review and analysis of existing literature on hydrogen bonding in the solid state.

Related Experiment Videos

  • Conceptual framework development to unify different types of hydrogen bonds.
  • Comparative analysis of electrostatic, covalent, and van der Waals contributions.

    • Main Results:

    • Identified common characteristics shared by a wide array of hydrogen bonds.
    • Demonstrated the continuum from strong electrostatic/covalent bonds to weak interactions.
    • Highlighted the significant role of dispersive-repulsive forces in weaker hydrogen bonds.

    Conclusions:

    • The term 'hydrogen bridge' better reflects the borderless and variable nature of these interactions.
    • These interactions exhibit a spectrum of covalent, electrostatic, and van der Waals content.
    • Understanding this spectrum is crucial for comprehending molecular interactions in solids.