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Combinatorial development of chiral phosphoramidite-ligands for enantioselective conjugate addition reactions
Oliver Huttenloch1, Eltepu Laxman, Herbert Waldmann
1Max-Planck-Institut für molekulare Physiologie, Abteilung Chemische Biologie, Otto-Hahn-Str. 11, 44227 Dortmund, Germany.
Chemical Communications (Cambridge, England)
|July 18, 2002
Abstract:
Chiral phosphoramidite ligands embodying bispidine frame work and a binaphthyl phosphoramidite for Cu-catalysed enantioselective conjugate addition reactions were developed employing principles of combinatorial and solid phase chemistry.