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Synthesis of a highly enantiomerically enriched silyllithium compound
Carsten Strohmann1, Jan Hörnig, Dominik Auer
1Institut für Anorganische Chemie, Universität Würzburg, Am Hubland, 97074 Würzburg, Germany. c.strohmann@mail.uni-wuerzburg.de
Chemical Communications (Cambridge, England)
|July 18, 2002
Abstract:
The highly enantiomerically enriched silyllithium compound lithiomethylphenyl(1-piperidinylmethyl)silane (4) reacts stereospecifically with chlorosilanes, but over a period of several hours slow racemization in solution at room temperature occurs, which can be suppressed by a transmetalation reaction with MgBr2(thf)4.