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Hypertension and narrowing of the renal arteries in infancy

W J Rahill1, A Molteni, K M Hawking

  • 1Department of Pediatrics, State University of New York at Buffalo, N.Y., USA.

The Journal of Pediatrics
|January 1, 1974
PubMed

Insights

Severe hypertension in infants due to renal artery stenosis can be treated surgically. While surgery improves blood pressure, some infants experience persistent mild hypertension, requiring further investigation.

Area of Science:

  • Pediatric Nephrology
  • Cardiovascular Surgery
  • Medical Research

Background:

  • Renovascular hypertension in infants, caused by renal artery stenosis, presents a significant clinical challenge.
  • Surgical correction of renal ischemia is a primary treatment option for this condition.

Observation:

  • Two infants with severe hypertension and renal artery stenoses underwent surgical correction.
  • Post-surgery, both infants experienced a significant drop in blood pressure but maintained mild hypertension for months.

Findings:

  • A review of 13 infants with renovascular hypertension showed a high mortality rate (4/4) without surgical intervention.
  • Persistent hypertension post-surgery, despite apparent relief of renal ischemia, was observed in this cohort.

Implications:

  • Surgical intervention for infant renovascular hypertension is critical for reducing mortality.
  • The underlying causes of persistent hypertension after surgical correction require further research.

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