Animal experimentation: the continuing debate

The use of animals in research and development has remained a subject of public debate for over a century. Although there is good evidence from opinion surveys that the public accepts the use of animals in research, they are poorly informed about the way in which it is regulated, and are increasingly concerned about laboratory-animal welfare. This article will review how public concerns about animal experimentation developed, the recent activities of animal-rights groups, and the opportunities and challenges facing the scientific community.