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pH-regulated formation of amyloid-like beta-sheet assemblies from polyglutamate grafted polyallylamine
Tomoyuki Koga1, Kazuhiro Taguchi, Takatoshi Kinoshita
1Nanoarchitectonics Research Center, National Institute of Advanced Industrial Science and Technology and CREST, Japan Science and Technology, Tsukuba Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan.
Chemical Communications (Cambridge, England)
|July 18, 2002
Abstract:
A novel artificial protein with simple primary structure, poly(gamma-methyl-L-glutamate)-grafted polyallylamine, has been prepared and the resultant peptide has shown a unique property of pH-regulated conformation and morphology.