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Bacterial Phylum Actinobacteria01:30

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Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...
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Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
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Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
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Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
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The pathophysiology of pneumonia involves the following steps:
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Related Experiment Video

Updated: Jan 3, 2026

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
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Laryngopharyngitis by Corynebacterium ulcerans.

D Kaufmann1, P Ott, C Ruegg

  • 1Dept. of Otorhinolaryngology, University Hospital of Zurich, Switzerland.

Infection
|July 18, 2002
PubMed
Summary

A rare case of diphtheria caused by Corynebacterium ulcerans occurred in Switzerland. Prompt antibiotic treatment led to a full recovery, highlighting the importance of considering C. ulcerans in diphtheria diagnoses.

Area of Science:

  • Infectious Diseases
  • Bacteriology
  • Public Health

Background:

  • Diphtheria, a serious bacterial infection, is typically caused by Corynebacterium diphtheriae.
  • Classical diphtheria symptoms include a sore throat, fever, and swollen glands, potentially leading to severe respiratory complications.

Observation:

  • A 71-year-old female presented with membranous laryngopharyngitis characteristic of classical diphtheria.
  • A toxigenic strain of Corynebacterium ulcerans was identified as the causative agent from the patient's throat swab.

Findings:

  • The patient received a 6-day course of amoxicillin-clavulanic acid.
  • Recovery was uneventful, with no reported complications following antibiotic therapy.

Implications:

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  • This case underscores the significance of Corynebacterium ulcerans as a potential cause of diphtheric laryngopharyngitis.
  • Clinicians should include C. ulcerans in the differential diagnosis for patients presenting with diphtheria-like symptoms, especially in regions where it is endemic.
  • This finding is crucial for accurate diagnosis and effective public health surveillance of diphtheria-like illnesses.