Related Experiment Video
Updated: Sep 30, 2026

Murine Prostate Micro-dissection and Surgical Castration
Published on: May 11, 2016
Self-castration
D Murphy1, M Murphy, R Grainger
1Department of Urology, St James's Hospital, Dublin, Ireland.
Background:
Deliberate genital self-mutilation is rare. Successful self-castration has been reported in a small number of individuals.
Method:
This study reports one such case of self-castration in a transsexual who was dissatisfied with waiting times for sex reassignment surgery (SRS).
Result And Conclusion:
The apparent triggering factor in this case appears to be depression related to the lengthy waiting times for SRS. As neither psychotherapy nor hormonal manipulation is successful, consideration should be given to improving the resources for patients with genuine gender dysmorphism.

