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Chromosome dynamics: new light on Aurora B kinase function
1University of North Carolina, Department of Biology, 607 Fordham Hall, CB#3280, Chapel Hill 27599-3280, USA.
Current Biology : CB
|July 18, 2002
Abstract:
Aurora B family kinases play an essential role in chromosome segregation and cytokinesis. Recent work suggests that the kinase activity is required for bipolar chromosome orientation, kinetochore assembly, spindle checkpoint and microtubule dynamics. Aurora B also has additional functions in chromosome condensation and cohesion.