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Updated: Aug 12, 2026

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
Published on: July 10, 2012
Perioperative care of the lung transplant patient
Alexander G Duarte1, Scott Lick
1Division of Pulmonary & Critical Care Medicine, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-0561, USA. aduarte@utmb.edu
Abstract:
Improvements in the perioperative management of lung transplant recipients have produced a 90% survival in the first 30 days following surgery. Detailed attention to donor organ procurement and preservation of the allograft are important in ensuring an early successful outcome. Early antibacterial administration based on donor or pretransplant cultures and antiviral therapy in CMV-negative recipients assist in avoiding early infectious complications. Development of hypoxemia or hemodynamic instability in the perioperative period requires a rapid, systematic evaluation with attention to mechanical, immunologic, or infectious causes. Nonpulmonary complications are not infrequent in lung transplant recipients.
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