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A modified molecular beacon combining the properties of TaqMan probe
De-Ming Kong1, Long Gu, Han-Xi Shen
1State Key Lab of Functional Polymer Materials for Adsorption and Separation, Chemical School, Nankai University, Tianjin 300071, China.
Chemical Communications (Cambridge, England)
|July 19, 2002
Abstract:
A modified molecular beacon that possesses a stem-hairpin structure as seen in conventional molecular beacons and can be cleaved during PCR in designed, and it can specifically recognize the presence of the target and was obviously more sensitive than conventional molecular beacons.