Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Aluminum: impacts and disease.

Prasunpriya Nayak1

  • 1Department of Physiology, Sikkim Manipal Institute of Medical Sciences, 5th Mile, Tadong, Gangtok, 737102, Sikkim, India.

Environmental Research
|July 19, 2002
PubMed
Summary

Aluminum exposure can negatively impact human health, affecting both the brain and other organ systems. This review summarizes aluminum

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Possible Association of Disturbances in the Estrous Cycle with Anxiety-related Behavior in Aluminum-exposed Female Rats.

Annals of African medicine·2026
Same author

Effects of growth factor application on germ cell architecture and oxidative stress handling in a rat model of testicular torsion-detorsion.

Journal of pediatric surgery·2026
Same author

Evaluating Remote Ischemic Conditioning in a Rat Model of Intestinal Ischemia Reperfusion: A Study Highlighting Experimental Model Limitations.

Journal of Indian Association of Pediatric Surgeons·2025
Same author

Comparison of Autonomic Indices in Normal Weight, Overweight and Obese Adults - a Comparative Analysis Using South East Asian Criteria for Obesity Classification.

Maedica·2025
Same author

High-fat Diet Coupled with Aerobic Exercise Has a Sexually Dimorphic Effect on the Biochemical Profile and Anxiety-like Behaviour of Adolescent Wistar Rats.

Annals of neurosciences·2025
Same author

Discovery of potential Leonurine-based therapeutic lead MJ210 attenuates Parkinson's disease pathogenesis via NF-κB and MAPK pathways: Mechanistic insights from in vitro and in vivo rotenone models.

European journal of medicinal chemistry·2025

Area of Science:

  • Environmental Health
  • Toxicology
  • Human Physiology

Background:

  • Aluminum is ubiquitous in the environment and widely used in daily life.
  • It enters the human body through diet, medication, and environmental exposure.
  • No physiological role for aluminum in the body is known, suggesting potential toxicity.

Purpose of the Study:

  • To comprehensively review the impacts of aluminum on human health.
  • To summarize and discuss aluminum's effects on major physiological systems.
  • To highlight the under-summarized effects of aluminum on extraneural tissues.

Main Methods:

  • Systematic literature review and synthesis of existing research.
  • Analysis of studies focusing on aluminum's effects on neural tissues.
  • Discussion of research pertaining to aluminum's impact on extraneural systems.

Main Results:

  • High brain aluminum levels are linked to neuropathologies, including structural, biochemical, and neurobehavioral changes.
  • Aluminum affects multiple extraneural systems: musculoskeletal, respiratory, cardiovascular, hepatobiliary, endocrine, urinary, and reproductive.
  • Adverse physiological effects are associated with aluminum accumulation in the body.

Conclusions:

  • Aluminum exposure poses a significant risk to human health.
  • Further research is needed to fully elucidate aluminum's toxicological profile across all physiological systems.
  • Understanding aluminum's impact is crucial for public health and risk assessment.

Related Experiment Videos