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Managing benign prostatic hyperplasia.

Pamela Dull1, Robert W Reagan, Robert R Bahnson

  • 1Department of Family Medicine at Ohio State University College of Medicine and Public Health, Thomas E. Rardin Family Practice Center, Columbia 43201, USA. dull-1@medctr.osu.edu

American Family Physician
|July 20, 2002
PubMed
Summary
This summary is machine-generated.

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Benign prostatic hyperplasia treatments range from medications like alpha blockers and 5-alpha-reductase inhibitors to surgical options. While some therapies offer rapid relief with side effects, others provide slower results or carry surgical risks.

Area of Science:

  • Urology
  • Pharmacology

Background:

  • Benign prostatic hyperplasia (BPH) treatment options have evolved.
  • Saw palmetto is a popular complementary therapy with fewer side effects but less efficacy than standard treatments.

Purpose of the Study:

  • To review current medical and surgical treatment options for benign prostatic hyperplasia.
  • To compare the efficacy and side effect profiles of various BPH therapies.

Main Methods:

  • Literature review of medical and surgical interventions for BPH.
  • Analysis of drug classes including alpha blockers and 5-alpha-reductase inhibitors.
  • Evaluation of surgical techniques such as transurethral resection of the prostate and minimally invasive procedures.

Main Results:

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  • Non-selective alpha blockers offer rapid symptom relief but can cause side effects; tamsulosin (a selective alpha blocker) has fewer side effects.
  • Finasteride and dutasteride (5-alpha-reductase inhibitors) reduce prostate volume but are less effective than alpha blockers, particularly for smaller prostates.
  • Surgery is an option for severe symptoms or treatment failure, with transurethral resection of the prostate being effective but carrying risks; newer minimally invasive procedures offer fewer complications but may require retreatment.

Conclusions:

  • A range of effective medical and surgical treatments exist for benign prostatic hyperplasia.
  • Treatment choice depends on symptom severity, patient risk factors, and individual preferences regarding efficacy and side effects.
  • Minimally invasive surgical options present a balance between reduced complications and potential need for retreatment.