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Updated: Sep 30, 2026

A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
[Distraction osteogenesis for treatment of temporomandibular joint ankylosis]
Cheng Liang1, Xing Wang, Biao Yi
1School of Stomatology, Peking University, Beijing 100081 China.
Objective:
To study the application of distraction osteogenesis in temporomandibular joint (TMJ) ankylosis patients.
Methods:
11 temporomandibular joint ankylosis patients (13 sides of TMJ) were treated by this technique. After removal of bony mass on the ankylosis area, a L-shape osteotomy of the ramus was performed to create the distraction transport disc which connected the mandible by distractor. Distractions were started on the 4 approximately 8th postoperative day. The distraction rhythm and rate were 0.25 mm 4 times a day. Distraction was stopped when contact was made between the transport disc and glenoid fossa. The patients underwent active mouth opening postoperatively. Distractor was kept in place for 3 approximately 4 months after completion of distraction and then removed under local anesthesia.
Results:
Postoperatively, the range of mouth opening of the 11 patients (13 sides) was increased to normal (33 approximately 45 mm), bone formation in the gaps were perfect and the neocondyle was remodeling and approximated normal shape. No complications were found.
Conclusion:
Distraction osteogenesis for arthroplasty has many advantages compared with traditional methods. It is valuable in clinical practice as a new method for treatment of TMJ ankylosis.
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