Amyloid beta-peptide induces cholinergic dysfunction and cognitive deficits: a minireview

Manh Hung Tran1, Kiyofumi Yamada, Toshitaka Nabeshima

  • 1Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Nagoya 466-8560, Japan.

Peptides
|July 20, 2002
PubMed
Summary

Alzheimer's disease involves amyloid beta-peptide (Abeta) causing brain dysfunction, including memory loss. Understanding Abeta's cellular actions and neurotoxicity mechanisms is key for developing Alzheimer's disease treatments.

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