Inhibitory effect of beta-hydroxyglutamic acid on a molluscan giant neurone

We found a spontaneously firing neurone, inhibited by beta-hydroxy(erythro)-L-glutamic acid, identified in the subesophageal ganglia of an African giant snail (Achatina fulica Férussac), although this neurone is not sensitive to L-glutamic acid. We suggest that beta-hydroxy(erythro)-L-glutamic acid may be a putative inhibitory synaptic transmitter of the identified molluscan neurone.