Related Experiment Video
Updated: Jan 31, 2026
03:42
Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis
Published on: March 15, 2024
1.2K
Retroperitoneal sarcomas: combined modality treatment approaches
Peter W T Pisters1, Brian O'Sullivan
1University of Texas, M. D. Anderson Cancer Center, Houston, Texas 77030-4009, USA. ppisters@mdanderson.org
Current Opinion in Oncology
|July 20, 2002
Summary
Retroperitoneal soft tissue sarcomas are rare. Achieving negative margins during surgery is challenging, leading to high recurrence rates. Combined modality treatments are under investigation for better outcomes.
Area of Science:
- Oncology
- Surgical Oncology
- Radiology
Background:
- Retroperitoneal soft tissue sarcomas are rare, comprising 15% of soft tissue sarcoma referrals.
- Surgical resection with negative margins is the standard of care but often difficult due to tumor size and advanced stage.
- These tumors have a high propensity for local recurrence and distant metastasis.
Purpose of the Study:
- To outline current concepts in the diagnosis, staging, and management of retroperitoneal sarcomas.
- To emphasize evolving combined modality treatment approaches.
- To highlight current investigational strategies for retroperitoneal sarcomas.
Main Methods:
- Review of current literature on retroperitoneal soft tissue sarcomas.
- Analysis of diagnostic and staging modalities.
- Evaluation of surgical and combined modality treatment strategies.
Main Results:
- Surgical resection is the primary treatment, but achieving negative margins is challenging.
- Local recurrence and distant metastasis are common complications.
- Combined modality treatments are being actively researched.
Conclusions:
- Management of retroperitoneal sarcomas requires a multidisciplinary approach.
- Evolving combined modality treatments offer potential for improved outcomes.
- Further research into investigational strategies is crucial for advancing patient care.
Related Concept Videos
01:16Combining Functions
238
Functions can be combined to form new mathematical models that describe interactions between variables. These combinations are fundamental in understanding relationships between changing quantities and are commonly encountered in scientific and engineering contexts. The combination methods—addition, subtraction, multiplication, division, and composition—each have unique implications for the resulting function’s domain and behavior.When combining functions through arithmetic...
238
01:15Sensory Modalities
3.9K
Sensation typically is the process by which the sensory receptors and sense organs detect stimuli from the internal and external environment and transmit this information to the central nervous system for processing.
General senses refer to the broad category of sensory information detected by receptors in the body and can be further grouped into somatic and visceral senses. Somatic sensations include touch, pressure, temperature, and pain and are essential for navigating our environment and...
General senses refer to the broad category of sensory information detected by receptors in the body and can be further grouped into somatic and visceral senses. Somatic sensations include touch, pressure, temperature, and pain and are essential for navigating our environment and...
3.9K
01:03Rous Sarcoma Virus (RSV) and Cancer
6.4K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
6.4K
01:20Frustration and Conflict: Approach-Approach, Approach-Avoidance
528
Frustration occurs when people are obstructed or prevented from achieving a desired goal or fulfilling a perceived need. For example, when someone's input is ignored in a discussion, it can lead to feelings of frustration. Conflict, however, arises from opposing interests, goals, or actions. Conflicts can take various forms based on the nature of these opposing desires or goals.
One common type of conflict is the Approach–Approach Conflict. In this case, a person faces two desirable...
One common type of conflict is the Approach–Approach Conflict. In this case, a person faces two desirable...
528
01:21Impedance Combination
751
Consider a string of christmas lights, each bulb symbolizing an impedance element. In this series configuration, the flow of electric current remains uniform across every component. This behavior aligns with Kirchhoff's Voltage Law (KVL), which asserts that the total impedance in such a setup equals the sum of individual impedances—akin to resistors in series. It follows that the voltage from the power source is distributed proportionally among these components, adhering to the voltage...
751
01:18Combination Of Resistors
3.8K
Electrical devices in any circuit can be connected either by series or parallel connections. Additionally, circuits can be connected involving both of these connections, known as combination or complex circuits. As these circuits have complex resistor connections, it is necessary to identify different parts as either series or parallel connections, then the whole combination of series and parallel resistors can be reduced to a single equivalent resistance. With the known equivalent resistance...
3.8K