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Updated: Sep 29, 2026

Atomic Absorbance Spectroscopy to Measure Intracellular Zinc Pools in Mammalian Cells
Published on: May 16, 2019
A case of Cronkhite-Canada syndrome whose major complaint, taste disturbance, was improved by zinc therapy
Shinya Yoshida1, Hiroshi Tomita
1Department of Otolaryngology, Nihon University School of Medicine, Tokyo, Japan.
Abstract:
A patient whose major complaint was taste disturbance and who was diagnosed as having Cronkhite-Canada syndrome was prescribed zinc sulfate. Improvement in taste disturbance was noted after 3 weeks of treatment, followed by gradual improvement in skin and gastrointestinal symptoms. Cronkhite-Canada syndrome can be considered a zinc-deficiency disorder caused by gastrointestinal polyposis.
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