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[Cerebral blood flow perfusion imaging by single photon emission computed tomography in patients with early syphilis]
Xin Shi1, Jinchang Wu, Zengli Liu
1Department of Dermatology, The Second Affiliated Hospital to Suzhou University, Suzhou 215004, China.
Objective:
To study the cerebral blood flow perfusion imaging by single photon emission computed tomography (SPECT) in patients with early syphilis.
Methods:
SPECT was performed with (99m)Tc-ECD as imaging agent on 32 patients with early syphilis and 15 healthy controls. Visual analysis was made.
Results:
Disseminated patchy radioactive rarefection mainly in cerebral cortex, suggesting hypoperfusion of regional cerebral blood flow, was shown in all patients. In particular 14 patients displayed multi-regional obvious hypoperfusion patches: 6 in left frontal lobe, 3 in right frontal lobe, 7 in left parietasal lobe, 6 in right parietal lobe, 11 in left temporal lobe, 5 in right temporal lobe, 3 in left occipital lobe, 3 in left basal ganglia, 1 in cerebellum, and 1 in intrecerebral nucleus. No abnormality was found in the controls.
Conclusion:
Cerebral blood flow abnormality exists in patient with early syphilis manifesting as patchy hypoperfusion in SPECT imaging.