Related Experiment Videos
Protein flexibility and drug design: how to hit a moving target
1Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, 428 Church Street, Ann Arbor, Michigan 48109-1065, USA. carlsonh@umich.edu
Current Opinion in Chemical Biology
|July 23, 2002
Abstract:
The most advanced methods for computer-aided drug design and database mining incorporate protein flexibility. Such techniques are not only needed to obtain proper results; they are also critical for dealing with the growing body of information from structural genomics.