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Updated: Jun 28, 2026

Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis
Published on: July 12, 2011
The epidemiology of peripheral vein infusion thrombophlebitis: a critical review
Vicky Tagalakis1, Susan R Kahn, Michael Libman
1Center for Clinical Epidemiology and Community Studies, Sir Mortimer B. Davis Jewish General Hospital, Montréal, Canada. vicky.tagalakis@mail.mcgill.ca
Abstract:
We critically assessed studies on the clinical importance, diagnosis, incidence, and pathogenesis of peripheral vein infusion thrombophlebitis, including catheter-related and patient-related risk factors. We reviewed the evidence linking thrombosis, particularly prothrombotic states such as the inherited thrombophilic disorders, with peripheral vein infusion thrombophlebitis. Peripheral vein infusion thrombophlebitis occurs in 25% to 35% of hospitalized patients with peripheral intravenous catheters and has both patient-related implications (e.g., sepsis) and economic consequences (e.g., extra nursing time). Although duration of catheterization, catheter-related infection, and catheter material are important risk factors for peripheral vein infusion thrombophlebitis, patient-related risk factors are not well elucidated.
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