The maze III surgical procedure
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Updated: Sep 30, 2026

Endoscopic Third Ventriculostomy and Pineal Biopsy from a Single Entry Point
Published on: June 28, 2024
1St. Thomas Health Services, Nashville, USA.
Abstract:
The maze III procedure is a surgical treatment for atrial fibrillation (A fib), a rhythm problem in which the heart's upper chambers (i.e., atria) beat rapidly and irregularly, sometimes beating more than 400 times per minute. Approximately 10% of Americans older than 60 years of age suffer from A fib. The maze procedure was designed to create a maze on the atria with multiple incisions that allow sinus rhythm to be conducted to the atrioventricular node without creating a reentry circuit. Currently, it is not a widely used procedure, but its popularity continues to increase. The maze III procedure generally is reserved as a treatment of last resort for a patient with A-fib that is unresponsive to medication therapy, electrical cardioversion, surgical ablation, or pacemaker implantation. The maze III procedure, performed as open-heart surgery, has a high success rate for sustaining normal heart rhythms, usually without the need for a pacemaker; however, all other medical and nonsurgical treatment options are exhausted before the maze III procedure is performed.
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