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Occupation and bladder cancer: a population-based, case-control study in Iowa
Tongzhang Zheng1, Kenneth P Cantor, Yawei Zhang
1Division of Environmental Health Science, Yale University School of Public Health, New Haven, Connecticut, USA. tongzhang.zheng@yale.edu
Journal of Occupational and Environmental Medicine
|July 24, 2002
Summary
Occupational exposures may increase bladder cancer risk. This study found higher risks for men in plumbing, auto mechanics, and painters, and for women in teaching and cleaning services.
Area of Science:
- Epidemiology
- Occupational Health
- Oncology
Background:
- Investigating occupation and industry's role in bladder cancer risk has yielded inconsistent findings.
- Strong evidence for increased bladder cancer risk is limited to few occupational groups.
Purpose of the Study:
- To investigate the association between occupational exposures and bladder cancer risk.
- To identify specific industries and occupations linked to increased bladder cancer incidence.
Main Methods:
- A large, population-based, case-control study in Iowa.
- Included 1452 bladder cancer cases and 2434 controls.
- Collected occupational history for jobs held ≥5 years since age 16.
Main Results:
- Men in plumbing, heating, air conditioning, rubber/plastic products, and motor vehicle parts industries showed increased risk.
- Occupations with elevated risk for men included supervisors, material movers, auto mechanics, painters, and machine operators.
- Women in secondary school teaching, record clerks, housekeeping, and laundry/dry cleaning services had significant excess risk.
Conclusions:
- Occupational exposures are suggested to play a significant role in bladder cancer risk.
- Identified specific industries and occupations associated with elevated bladder cancer risk warranting further investigation and preventive measures.